The benefits of Cistanche tubulosa are undeniable, and its effects on the brain can be truly remarkable.
From increased memory to improved focus, this plant has been shown in studies to offer a wide range of cognitive benefits.
In this article, we will explore some of the most significant advantages that come from taking Cistanche tubulosa as a Nootropic.
So without further ado, let's just get straight into it, shall we?
First things first, what is Cistanche tubulosa?
Cistanche tubulosa is a parasitic plant that grows in the deserts of China, Mongolia, and Siberia.
It is an adaptogen due to its ability to increase resistance against stressors such as environmental factors or infections by fungi, bacteria, or viruses.
This herb has been used for centuries as both food and medicine throughout these regions.
Cistanche tubulosa extract (CTE) is a commonly utilized medicinal in the treatment of leucorrhea, profuse metrorrhagia, end-stage renal disease, constipation, impotence, and infertility.
Cistanche tubulosa is made up of chemical components that include:
Non-volatile phenylethanoid glycosides (PHGs)
Iridoids
Lignans
Volatile oils
Alditols
Oligosaccharides, and polysaccharides
Echinacoside, a component found in this herb, has been shown to protect damaged fibroblasts by lowering ROS levels.
ROS levels, which means Reactive Oxygen Species, are molecules that contain an unpaired electron in the outer shell.
These unpaired electrons make ROS highly unstable and reactive.
ROS damages cells via oxidative stress which leads to cell death, premature aging of tissues or organs, cancerous growths and even diseases such as Alzheimer's disease.
Cistanche tubulosa can be utilized to aid in the treatment of this condition.
It contains antioxidant, vasorelaxation, and anti-inflammatory properties in addition to neuroprotection and osteoporosis prevention.
Cistanche tubulosa extract works as an adaptogenic
Cistanche tubulosa extract also has an adaptogenic effect which increases the body's resistance to physical and mental stress.
Adaptogens work to counteract the effects of stress in the body.
Extreme stress can result in serious physical changes, such as damaging the neurological, endocrine, and immune systems.
Adaptogens have stimulant effects that help to offset the negative consequences of this.
Studies have shown that CTE improves the general condition of animals suffering from chronic fatigue, cold exposure, and aging by reducing oxidative damage in organs such as the liver, heart, and brain tissues.
CTE is also able to increase the lifespan of mammals, and it has been used to decrease fatigue in athletes.
What are the benefits?
When it comes to the benefits of Cistanche tubulosa, this herb's abilities to increase memory and focus are truly remarkable.
One particular study showed that a dose-dependent improvement in short-term working memory was noted after taking a Cistanche tubulosa extract.
Another study also concluded that there were significant improvements in attention, executive function, and processing speed in participants after taking Cistanche tubulosa extract.
An amazing benefit of this herb is its ability to improve memory recall which can be helpful for those suffering from Alzheimer's disease or other conditions that cause memory loss.
Cistanche tubulosa appears to exert positive effects on neuronal regeneration by promoting neurite growth in primary neurons.
A study conducted on mice showed that Cistanche tubulosa extract improved cognitive function and reduced neuronal damage following ischemic injury.
Cistanche has also been shown to enhance immune function and reduce pro-inflammatory cytokines.
What are the side effects?
People who take Cistanche tubulosa extract do not typically experience any side effects.
However, since this herb can have a stimulant effect in the body similar to caffeine, it may cause insomnia or restlessness for those who are sensitive to these types of herbs if taken too late in the day.
Cistanche has been shown to be safe even in high doses when used for short periods of time.
For those people who do experience insomnia from taking Cistanche tubulosa extract, they can take it earlier in the day as opposed to later.
What to look out for in a Cistanche tubulosa supplement?
Make sure that the product you buy is free from fillers, additives, and binders like magnesium stearate which has been shown to block nutrient absorption by the body.
Look for an organic Cistanche tubulosa supplement that uses minimal processing to retain the natural phytochemicals found in this herb.
Check for a standardized extract to ensure that you get the right dosage.
Also, check into whether or not your supplement uses alcohol in its extraction process as this can damage beneficial compounds found within Cistanche tubulosa.
What is the best dosage?
The recommended dose of Cistanche tubulosa extract is 200-400 mg taken once a day.
If you're just starting out with Cistanche tubulosa, it's best to start with a lower dose in order to gauge your tolerance.
I would even suggest going lower than 200 mg if you are sensitive to stimulants, splitting the dosage into two doses before gradually increasing it.
I would take 100 mg in the morning and then 100 mg at around noon.
You can always increase the dosage if needed later on by taking more than one pill per day.
What I like about Cistanche tubulosa extract
I have only experimented with Cistanche tubulosa extract for a very short period of time but I have already noticed its effects on my mood, focus, and cognition.
I take 200 mg once a day and first thing in the morning.
When I take Cistanche tubulosa, it has a great effect on my mood and I feel more in the zone throughout the day which makes me more productive at work.
Now keep in mind that I also take L-theanine and caffeine, so it's hard for me to say that Cistanche tubulosa has these effects on me by itself.
That being said, I have definitely noticed that when I go to make a mental note of something important during my day, I am able to recall it way more easily.
I can't say that I am experiencing any side effects with this herb but at the same time, my goal is not for Cistanche tubulosa extract to be a long-term supplement in my regimen.
My reason for experimenting with extracts of herbs like these is because they are very potent and can be effective for short periods of time.
I plan on cycling Cistanche tubulosa with other nootropics so that I can get the most out of them without building up a tolerance or experiencing side effects over an extended period of time.
If I find a 'magic combination/stack' I will make sure to keep you updated here.
FAQ
What is Cistanche tubulosa good for?
Cistanche tubulosa has long been used for increasing immunity, sexual health, antioxidant activity, and neuroprotection.
What is Cistanche Tubulosa Extract (CTE)?
Cistanche tubulosa is a parasitic plant with the ability to improve memory, immunity, and sexual performance, as well as cure impotence and constipation.
Does Cistanche Tubulosa Extract increase testosterone?
Echinacoside from Cistanche tubulosa, and Cistanche tubulosa itself, have been found to substantially boost testosterone synthesis in studies, owing to increased expression of key steroidogenic enzymes.
Uridine monophosphate (UMP) is a naturally occurring nucleotide that can help increase mental energy, brainpower, and focus.
It also helps to repair the protective sheath around neurons called myelin.
Uridine supplements are used by people who want to improve their memory and cognitive abilities in order to be more productive both at work or school or just in everyday life!
This blog post will go over the 10 benefits of uridine monophosphate as a nootropic supplement. So without further ado, let's just get straight into it, shall we?
First things first, what is Uridine Monophosphate?
The pyrimidine nucleoside, uridine monophosphate (also known as 5′-uridylic acid), is found in all living organisms, from humans to bacteria.
Uridine is a nucleoside that occurs in RNA (ribonucleic acid) as one of four repeating components.
RNA and DNA (deoxyribonucleic acid) are the major information carriers in each of your cells.
Uridine is so essential to brain growth that it is included in human infant formulas.
Uridine is a crucial precursor in the creation of neurotransmitters, particularly important for memory and cognitive function.
There are many benefits to using uridine monophosphate as a cognitive enhancer or nootropics.
Let's take a quick look at 10 of the most important benefits of using Uridine Monophosphate below.
10. Better brain function
When taken as a nootropic supplement or cognitive enhancer it boosts neurotransmission between cells, this leads to better brain health overall!
Uridine Monophosphate can help with memory formation by increasing dopamine receptor density.
It also helps to repair the protective sheath around neurons called myelin, which is important for cognitive function and overall brain health!
Uridine Monophosphate stimulates the growth of new mitochondria in your cells as well.
This leads to better energy levels throughout the day, which results in increased productivity.
9. Reduces stress
Taking Uridine Monophosphate supplements can help reduce the harmful effects of cortisol in your body.
This is important because high levels of cortisol in the body lead to increased weight gain, anxiety, and depression!
Using a nootropic supplement like this one helps to balance out hormone levels naturally.
In addition, high cortisol levels have been shown to damage brain cells and can lead to memory impairment.
It also damages nerve endings in the hippocampus region of your brain which results in a loss of cognitive function over time!
This is why it's so important for people who are stressed out all the time or suffer from anxiety disorders to take Uridine.
8. Better sleep quality
Taking Uridine Monophosphate before bed can help to improve your sleep quality by increasing dream lucidity.
When you take this supplement, it helps stimulate the release of dopamine in your brain while you're sleeping at night!
This results in more vivid dreams and better REM sleep cycles overall.
People who struggle with insomnia can benefit from using Uridine Monophosphate as a nootropic supplement.
It also helps to decrease your heart rate and calm down any muscle tension you may have in your body before going to bed at night too.
This is why it's so beneficial for people who are anxious or stressed out all the time because they tend to struggle with poor sleep quality.
Uridine Monophosphate is a great nootropic for this reason because it can help you to get better, more restorative sleep!
7. Improved cell health
This supplement has been shown to help protect neurons from damage and improve cellular membrane fluidity.
In addition, it helps to stimulate the creation of new mitochondria in your cells which leads to increased ATP synthesis!
Uridine Monophosphate is a nucleotide that's found naturally occurring in our bodies as well as foods like seafood, dairy products, and organ meat.
It's necessary for the production of ATP which is used as energy by cells throughout the body!
This supplement can help to regulate metabolism in your cells plus repair damaged mitochondria that have been caused by extreme stress or lack of sleep too.
When you're using Uridine Monophosphate as a nootropic supplement, it's important to make sure you're getting enough choline in your diet too.
This is because these two compounds are naturally occurring together and work synergistically when taken together!
Uridine Monophosphate also helps the body produce new phospholipids which are necessary for proper cell function too.
6. Improved cardiovascular health
Uridine Monophosphate helps to reduce blood pressure and triglyceride levels in your body.
In addition, it also increases HDL cholesterol which has been shown to be protective against heart disease!
This supplement is a great choice for people who suffer from hypertension or other heart conditions that put them at risk of developing cardiovascular disease.
When you're taking this nootropic, it's important to talk with your doctor first to make sure that there aren't any other medications or supplements you should avoid too!
Uridine Monophosphate is a nucleotide and helps the body repair its own DNA.
It also helps to regulate inflammation in the body which can help to reduce your risk of developing other chronic diseases too.
5. Improved nervous system function
Another benefit of Uridine Monophosphate is that it helps the body to produce new nerve growth factors which result in improved neurotransmitter activity!
This supplement can help increase your levels of acetylcholine, dopamine, serotonin, and GABA too.
In addition, this nootropic has been shown to help protect the brain from degenerative diseases like Alzheimer's and Parkinson's.
Uridine Monophosphate is one of several compounds that are necessary for the production of phosphatidylcholine in your body which can be used to repair nerve damage throughout your nervous system!
This supplement helps with cell structure growth, connectivity, and repair as well.
When you're looking for a nootropic supplement to help with these benefits, Uridine Monophosphate is definitely one of the best choices out there!
In fact, it's been shown to be even more effective than CDP Choline and Alpha GPC when taken on its own too.
So if you're looking to improve your focus, motivation, and memory with a nootropic supplement that's also all-natural - Uridine Monophosphate may be the perfect choice for you!
4. Improved memory
Uridine Monophosphate has been shown to help improve working memory and long-term cognitive function.
This supplement boosts ATP which is necessary for healthy neuron activity in the body too.
It's also a great choice if you're looking for improved mental clarity, focus, motivation, mood stabilization, stress management, and attention to detail.
In addition, this nootropic may help improve your ability to learn new things and make it easier for you to recall memories from the past too!
3. Improved mood
Another great benefit of Uridine Monophosphate is that it helps to improve your overall mood as well as reduce anxiety and depression.
It's been shown to help boost dopamine, serotonin, and GABA levels in the body which can drastically improve how you feel!
In fact, this nootropic has even been used clinically to help treat cases of severe depression and anxiety in adults!
In addition, this supplement helps to boost your energy levels which can also contribute to a better mood overall.
When you're looking for a nootropic that's going to improve how you feel both physically and mentally - Uridine Monophosphate may be the perfect choice for you!
2. Improved energy levels
Uridine Monophosphate is one of the best natural supplements you can take to improve your overall energy levels.
Specifically, this supplement works by helping boost ATP which provides cells with their primary source of cellular fuel!
In fact, research shows that when taken on its own Uridine Monophosphate can increase ATP levels much more effectively than similar nootropics like CDP Choline or Alpha GPC.
In addition, this supplement helps to boost your energy in a safe and natural way without the crash that's common with many other supplements too!
1. Crosses the blood-brain barrier (BBB) easily
The main reason Uridine Monophosphate is such a popular nootropic choice among people worldwide is that it's able to cross the blood-brain barrier with ease.
This supplement helps improve cell membrane function which can result in improved communication between your brain cells!
In addition, this supplement boosts levels of acetylcholine which is the main neurotransmitter that's responsible for memory, learning, and attention to detail.
The blood-brain barrier is a semi-permeable membrane that prevents solutes in the circulating blood from non-selectively entering into the extracellular fluid of the central nervous system, where your neurons are.
What this means is that when you take a nootropic that's able to cross the blood-brain barrier it can have a much more positive effect on your cognitive abilities, mood, and mental clarity since it's able to directly influence your brain tissue.
Bottom Line
Uridine Monophosphate is a nootropic supplement that helps to improve a variety of cognitive functions and benefits.
Specifically, this natural supplement improves ATP production in the body which can provide your cells with better energy levels for improved brain function too!
In addition, Uridine Monophosphate is great at crossing the blood-brain barrier and has been shown to boost levels of acetylcholine as well as dopamine, serotonin, and GABA - which all contribute to better mood & motivation!
Uridine Monophosphate can be bought for a decent price online and comes in the form of powder or capsules.
Your brain is a complex organ that controls everything from breathing to mood. As such, there are many ways you can improve its function with the right supplements.
One of these supplements is Hordenine HCL, which has been shown to help memory and cognitive function!
In this article, we will explore the benefits of Hordenine for improving cognitive enhancement as well as how it works in the body to help improve your brain function.
What is Hordenine HCL?
Hordenine HCL, also known as N,N-dimethyltyramine, is a natural compound found in many different types of plants including barley and bitter orange.
It's a phenethylamine-type alkaloid which means it has a chemical structure similar to compounds like dopamine and norepinephrine.
Hordenine HCL is an analog of these two neurotransmitters, which means that it can be mistaken for them by the enzymes in your body as they all have very similar structures.
However, unlike those other molecules, hordenine actually inhibits the enzymes that break down dopamine and norepinephrine.
By blocking these enzymes, hordenine HCL effectively increases levels of neurotransmitters like dopamine in your brain which can lead to improved memory function!
What are the benefits?
There are many benefits to Hordenine HCL and they all stem from the fact that hordenine acts as a powerful Nootropic.
Hordenine can improve cognitive abilities including memory, focus, attention span, and logical reasoning.
It's also been shown to increase physical endurance by helping the body convert food into energy more efficiently.
There is even some research that suggests that hordenine may help improve mood by increasing levels of serotonin and dopamine in the brain!
What are the side effects?
When taken at the right dosage, Hordenine HCL is a very safe nootropic that can provide many benefits for cognitive enhancement.
However, if you take too much it's possible to experience some side effects including nausea and high blood pressure so make sure not to exceed 100mg of hordenine per day!
In addition, it's also possible to experience some side effects if you take hordenine with caffeine as they both come from a similar chemical family.
The right dosage should be 50mg to 100mg per day and it should not be mixed with other stimulants like caffeine or any monoamine oxidase inhibitors (MAOIs).
In some rare cases, Hordenine HCL has induced seizures in people so it should not be taken if you suffer from a seizure disorder.
What's the optimal dosage?
As briefly mentioned above, the right dosage of Hordenine HCL is 50mg to 100mg per day.
It can be taken in one dose or split into two doses separated by a few hours with each dose being about 25mg to 50mg so it's important not to exceed this recommended range!
The best way to experience the benefits of Hordenine HCL is to buy a supplement that contains 100 mg per serving and then split this into two doses of 50mg separated by hours.
It's worth noting that Hordenine HCL has a short half-life (3-5 hours) and its effects will usually peak at around one hour after taking it.
What I like about Hordenine HCL
I have only used Hordenine HCL twice but I really liked what it did for my cognitive abilities.
One of the benefits I immediately noticed was its stimulatory effect which was very clean and without any jitters or energy crashes.
I also noticed that Hordenine HCL helped me feel more engaged in conversations, whether they were work-related or personal.
It also made it much easier for me to focus on the content of what people were saying which is helpful when you're actively trying to solve problems.
When taking 25 mg to 50 mg I experienced zero side effects. When I took 100 mg I experienced nausea and some jitters.
I also had a headache after taking 100 mg which is an effect that I've experienced in the past when combining caffeine with Modafinil or other similar stimulants.
While neither of these side effects was too severe, they are worth noting for anyone who plans to take Hordenine HCL daily.
In order to combat these side effects, I usually take a bottle of water with me + some electrolytes (Potassium chloride, Sodium chloride, Sodium Bicarbonate, and Magnesium Sulphate).
Where can I buy Hordenine HCL?
Hordenine is a naturally occurring compound that has been used in traditional medicine for centuries so it's readily available online and in specialty stores across the globe.
The best way to find quality supplements containing hordenine is by buying one from a reputable supplier who is transparent about their ingredients and provides lab reports as proof.
I personally bought mine from PeakNootropics. That being said, I have recently replaced most of my Nootropics with Mind Lab Pro where I get more bang for my buck.
Mind Lab Pro has 11 nootropic ingredients including Bacopa Monnieri, L-Theanine, and Phosphatidylserine which have similar effects as Hordenine HCL.
It's not cheap but it has a lot of great reviews which is why I decided to give it a shot.
Bottom Line
Hordenine HCL is a naturally occurring stimulant that can be used to improve mental function and physical energy.
It's best taken at doses of 25mg to 50mg per day split into two separate servings so it would be wise not to exceed 100mg in total on any given day.
Hordenine HCL is generally safe but may induce nausea and jitters at high doses.
Hordenine HCL is readily available online and can be bought from reputable suppliers that provide lab reports to prove the quality of their products.
In this article, I'll take a closer at the 8 best over-the-counter nootropics. I'll also cover the potential risks and side effects you may run into and the benefits you can expect.
Are you looking for ways to increase your mental performance?
If so, you may want to consider trying nootropics – supplements designed to improve cognitive functions. Nootropics have become increasingly popular in recent years. They can provide several potential benefits, such as improved focus and memory, increased learning capacity, enhanced productivity, and better overall brain health.
But, with such a wide variety of products on the market, it can be difficult to decide which one is best for you. That’s why I’ve compiled a list of the 8 best over-the-counter nootropics available in 2023.
Let's take a look at these 8 nootropics down below.
The best over-the-counter nootropics, according to scientific evidence, are:
Nooceptin
Vyvamind
Caffeine
L-Theanine
Creatine
Rhodiola Rosea
Panax ginseng
Bacopa Monnieri
1. Nooceptin
Ignite your mental potential! FDG-117, known as Nooceptin, is an amazing nootropic blend designed to give you a competitive edge.
Its combination of nootropic ingredients is scientifically proven to boost cognitive performance and energy levels for extraordinary focus and clarity - a must-have in today's fast-paced world.
Nooceptin combines 7 carefully-selected clinically researched nootropic ingredients to create a powerful brain enhancer.
Lion's Mane Mushroom Extract - 400 mg (30% polysaccharides)
Panax Ginseng Extract - 200 mg
By stacking together Ginkgo Biloba, L-Theanine, Citicoline, and Rhodiola Rosea, you can dramatically enhance your cognitive performance while achieving maximum energy levels.
Adaptogens like Ginkgo help the body cope with stress effectively, as L-Theanine promotes a state of relaxed alertness. Meanwhile, research has shown that Citicoline[1] and Rhodiola Rosea can increase concentration capabilities, memory, and learning for peak focus.[2]
So if you're looking for a comprehensive brain supplement to help you out, Nooceptin is my clear winner.
Nooceptin Pros
Combines 7 all-natural nootropic ingredients
Increases cognitive performance and energy levels
Improves focus and clarity
Nooceptin Cons
Shipping times can take up to 2 weeks
Nooceptin in Summary
If you're looking for a comprehensive nootropic supplement to boost your mental performance, I'd recommend Nooceptin. With its carefully selected ingredients, you can expect increased focus and clarity while achieving maximum energy levels.
You can maximize your cognitive potential by properly stacking the right combination of nootropics, so why not give Nooceptin a try? It's an amazing way to get ahead in today's world!
2. Vyvamind
At the heart of Vyvamind (NSV-313) lies a carefully curated blend of 6 all-natural nootropic ingredients, working in synergy to provide powerful cognitive enhancement.
The Vyvamind ingredients are:
Vitamin B6 (2.5 mg)
Vitamin B12 (50 mcg)
L-Tyrosine (300 mg)
Citicoline (CDP Choline) - 200 mg
L-Theanine (150 mg)
Caffeine Anhydrous (75 mg)
Numerous clinical studies support each ingredient's efficacy – unlocking and enhancing your brain's potential!
CDP Choline is an exciting supplement that provides a window into our cognitive potential. It serves as the key precursor to Acetylcholine (ACh), enabling replenishment of this essential neurotransmitter to improve learning and memory formation while also conferring neuroprotection - proven effective against Alzheimer's Disease and other neurological maladies.[3]
L-Tyrosine is a powerful amino acid that assists in boosting brain performance! It helps to increase alertness and vigilance while stimulating the production of dopamine, norepinephrine, and epinephrine.
Elevating these neurochemicals has greatly enhanced one's overall cognitive abilities - making it essential for those seeking peak mental function.[4]
L-Theanine is an incredible amino acid that offers a rare combination of relaxation without sleepiness. It can lessen stress and amplify attentiveness, contributing to improved brain functioning.
And when combined with Caffeine Anhydrous - you get alertness and acuity sans the unpleasant side effects like a racing heart or post-crash slump.[5]
By incorporating these nootropic ingredients into Vyvamind, we get something greater than its individual parts that significantly powers up cognitive performance while helping maintain mental clarity at peak conditions.
Vyvamind Pros
Combines 6 all-natural nootropic ingredients
Increases cognitive performance and energy levels
Improves focus, clarity, and alertness
Completely legal and can be bought over-the-counter (OTC)
Vyvamind Cons
Not ideal for people on a tight budget
Vyvamind in Summary
Vyvamind is an amazing nootropic blend that combines 6 all-natural ingredients to provide powerful cognitive enhancement. It boosts mental performance and energy levels, allowing you to achieve maximum clarity and focus while remaining alert and attentive.
If you’re looking for a comprehensive natural supplement to help improve your mental abilities, Vyvamind is an excellent choice. It’s a great way to maximize your cognitive potential and get ahead in life!
3. Caffeine
Caffeine is a powerful nootropic that primarily blocks adenosine receptors in the central nervous system, increasing energy, alertness, and focus.[6]
Blocking these receptors prevents adenosine from binding to them and increases the release of the neurotransmitter acetylcholine (ACh). This allows for higher levels of communication between neurons, leading to enhanced cognitive performance.
At the same time, caffeine also acts as an inhibitor of phosphodiesterase (PDE), which is responsible for breaking down cyclic AMP (cAMP) molecules in cells. By inhibiting PDE activity, caffeine increases cAMP levels throughout the body, allowing for increased alertness and mental agility.[7]
Caffeine has an advantage over other popular nootropics due to its molecular structure: it has a three-dimensional shape (1,3,7-trimethylxanthine) similar to adenosine. This allows it to bind and block adenosine receptors more than its closest structural relatives, like theobromine or theophylline.
Additionally, caffeine may have some unique effects on dopamine production and metabolism.
It appears to increase dopamine synthesis while simultaneously preventing dopamine release from vesicles in brain cells – a phenomenon known as ‘reverse transport’ – resulting in heightened dopamine signaling within neural pathways.
From improved alertness and faster reaction times to increased motivation and enhanced mood, caffeine has been scientifically proven as an effective cognitive booster.
Let it unlock the full potential of your mental energy by allowing you to tackle whatever challenge comes ahead effortlessly!
Caffeine Pros
Readily available over-the-counter
All-natural and robust scientific evidence
Relatively inexpensive
Can increase alertness and focus
Increases motivation and energy levels
Caffeine Cons
It can cause insomnia and jitters in high doses
Some people are extremely caffeine sensitive
Caffeine in Summary
One of the most consumed stimulants in the world, caffeine has been shown to boost alertness and focus reliably. It can provide an effective cognitive boost without unpleasant side effects when used judiciously.
It is one of the most reliable over-the-counter nootropics on the market. It should be considered part of a comprehensive nootropic stack for anyone looking for an edge.
4. L-Theanine
L-Theanine works in the brain by increasing levels of GABA, a neurotransmitter that helps to reduce anxiety and improve mood. By stimulating the production of alpha waves in the brain, L-theanine can also help with relaxation and focus.[8]
This is why it is considered a great over-the-counter nootropic because it provides mental clarity without being overly stimulating like other nootropics.
Unlike other nootropics, L-theanine does not cause unwanted side effects like restlessness or jitteriness. It has been proven safe and effective in numerous studies, making it a popular choice among those who want to enhance their cognitive functioning without sacrificing their physical or mental well-being.
L-theanine's ability to cross the blood-brain barrier (BBB) quickly and very efficiently makes it so powerful. This means it can reach the brain much faster than many other supplements and start working almost immediately.
It also does not require significant doses for effectiveness, which can make it more economical than some other supplements on the market.
In addition to its calming effects on both body and mind, L-theanine has also been shown to have antioxidant properties that help protect cells against damage from free radicals.[9]
L-Theanine Pros
Can reduce anxiety
Increases mental clarity and focus without jitters
Improves mood
Provides antioxidant protection
It does not require large doses for effectiveness
It can be bought over the counter in most stores
L-Theanine Cons
High dosages can cause drowsiness in some people
L-Theanine in Summary
L-theanine is a great over-the-counter nootropic that can provide mental clarity and focus without jitters. It has been proven to reduce anxiety and improve mood while providing antioxidant protection.
It is also available in most stores, making it an ideal choice for those looking for a natural way to enhance their cognitive functioning without spending a lot of money.
5. Creatine
Creatine Monohydrate is best known for its ability to help build muscle, but it can also be used as a nootropic. Creatine has been found to have a positive effect on the brain. Studies have shown that creatine can improve memory, focus, and overall mental performance.[10]
Creatine works in the brain by increasing levels of phosphocreatine, which helps to produce energy molecules called ATP (adenosine triphosphate). This increased energy production helps to improve brain function and mental performance.
In addition to improving cognitive function, creatine has also been found to reduce fatigue and stress. It can help increase alertness and concentration while reducing anxiety and depression.
A study revealed an innovative way to combat mental fatigue - taking creatine. This scientific study used a double-blind placebo-controlled experiment and found that 8 grams of creatine each day for 5 days resulted in improved oxygen utilization by the brain during mathematical tasks.[11]
Near-infrared spectroscopy (NIRS) confirmed this finding, suggesting that increased oxygen consumption leads directly to decreased exhaustion levels.
Creatine is an effective OTC nootropic that can help improve cognitive function in healthy individuals and those with neurological disorders. It is generally considered safe when taken in recommended doses and is readily available in most health stores.
Creatine Pros
Robust scientific evidence of cognitive enhancement
Increases energy production in the brain
Can reduce mental fatigue
Improves memory, focus, and overall mental performance
Reduces anxiety and depression
Creatine Cons
Not ideal for people with kidney dysfunction
Creatine in Summary
Creatine is a great over-the-counter nootropic that can help improve mental performance, reduce fatigue, and increase alertness. It has been clinically proven to improve cognitive function in healthy individuals and those with neurological disorders.
Creatine is relatively inexpensive and easy to obtain, making it an ideal choice for people looking for an affordable way to improve their mental clarity without spending a lot of money.
6. Rhodiola Rosea
Rhodiola Rosea is an adaptogenic herb that can help improve mental performance, reduce fatigue, and increase concentration. It has been used for centuries to treat stress and depression and enhance physical performance. It's a natural nootropic that is available OTC in most health stores.
Through a meticulous review of 10 research papers, one study determined that Rhodiola rosea (RR) supplementation could be used to enhance physical exercise capacity significantly.[12]
The vast majority of the studies analyzed concluded that Rhodiola rosea had an advantageous influence on sports activities and competition outcomes, with no significant side effects detected.
Subjects taking Rhodiola rosea also showed a reduction in pain and muscle damage after exercise training, improved skeletal muscle damage, enhanced antioxidant capacity, reduced oxidative stress, reduced RPE scores, and improved athletic and explosive power.
Rhodiola Rosea Pros
An all-natural adaptogenic herb
Reduces fatigue
Improves cognitive function and physical performance
Reduces stress and depression
Rhodiola Rosea Cons
It can take weeks to kick in fully
Rhodiola Rosea in Summary
Rhodiola Rosea is an adaptogenic herb that can help improve mental performance, reduce fatigue, and increase concentration. It has been used for centuries to treat stress and depression and enhance physical performance. Taking it OTC in recommended doses is generally considered safe and is an ideal choice for people looking for a natural nootropic with few side effects.
7. Panax Ginseng
Panax Ginseng is an adaptogenic herb used for centuries in traditional Chinese and Korean medicine. It is also known as Asian ginseng, Chinese ginseng, Japanese ginseng, or Korean ginseng. As an OTC nootropic, Panax Ginseng helps to improve cognitive function, increase alertness and focus, reduce stress levels, and improve mood.
The active ingredient in Panax Ginseng is the saponin called ‘ginsenosides,’ which increases acetylcholine release (ACh) and stimulates nerve growth factor production.[13]
This helps to improve neural communication and therefore enhances memory capacity and concentration. Studies have also shown that Panax Ginseng increases dopamine activity in the brain's reward pathways, leading to improved well-being and motivation.[14]
Panax Ginseng strengthens the immune system by increasing natural killer cells responsible for fighting off invading organisms or viruses. This can help protect against common colds and flu symptoms. It also has anti-inflammatory properties, which can help reduce muscle soreness after exercise.
Panax Ginseng Pros
Improves cognitive function
Increases alertness and focus
Reduces stress levels
Enhances well-being and motivation
Strengthens the immune system
Panax Ginseng Cons
Not all brands are equally effective
Panax Ginseng in Summary
Panax Ginseng is an adaptogenic herb that can be taken OTC to improve cognitive function, reduce stress levels, and strengthen the immune system. It has anti-inflammatory properties and helps increase dopamine activity in the brain’s reward pathways.
8. Bacopa Monnieri
Bacopa Monnieri is an over-the-counter nootropic used for centuries to improve cognitive function. It increases nerve impulses in the brain, which boosts its capacity for learning, memory, and knowledge retention.
Research has shown that Bacopa Monnieri can help improve reaction time, logical reasoning, and thinking processes in those who take it regularly.[15]
Regarding cognitive enhancement, Bacopa Monnieri works by increasing acetylcholine levels in the brain.[16] Furthermore, Bacopa Monnieri has antioxidant properties that protect the brain from free radical damage due to environmental toxins or aging.[17]
Bacopa Monnieri is an effective over-the-counter nootropic due to its ability to improve mental clarity and focus while providing antioxidant protection for the brain against environmental stressors and aging.
Taking this supplement regularly can provide users with improved memory formation and recall along with enhanced reaction time and logical processing capabilities - all of which are beneficial when needing to stay sharp throughout any task or activity!
Bacopa Monnieri Pros
Improves cognitive function
Increases nerve impulses in the brain
Promotes memory formation and recall
Provides antioxidant protection against aging and environmental toxins
Bacopa Monnieri Cons
It can take weeks for results to be noticed
Bacopa Monnieri in Summary
Bacopa Monnieri is an over-the-counter nootropic used for centuries to improve cognitive function. It increases nerve impulses in the brain, which boosts its capacity for learning, memory, and knowledge retention. Additionally, it can help improve reaction time, logical reasoning, and thinking processes while providing antioxidant protection against aging.
What Are the Best Over-the-Counter Nootropics?
The best over-the-counter nootropics, according to my research, are:
Nooceptin
Vyvamind
Caffeine
L-Theanine
Creatine
Rhodiola Rosea
Panax ginseng
Bacopa Monnieri
My list contains a mix of tried and tested nootropics that have been proven effective in improving cognitive functions. Each has different mechanisms of action and can provide users with a wide range of benefits.
That said, they are all readily available over the counter and can be used to enhance your mental performance without the need of a prescription.
Ultimately, I believe that incorporating a combination of these nootropics into your everyday routine is essential for optimal cognitive performance. With regular usage, you’ll find yourself more focused and energized - ready to take on whatever life throws you!
How to Choose the Best Over-the-Counter Nootropics?
Choosing the best over-the-counter nootropics can be a tricky task.
You want to ensure you get the most out of your supplement while avoiding negative side effects.
The first step is to research each nootropic and identify what it does, its mechanism of action, and potential side effects. This will help you make an informed decision and avoid any nasty surprises.
Next, identify which nootropics are most suitable for the cognitive functions you’re looking to improve and consider which ones may work best together for your needs. If a combination of supplements is what you're after, it's important to look for potential interactions between them.
If you're brand new to the world of nootropics, then I suggest starting with a nootropic blend like Nooceptin, which is easily available online. This blend can provide you with the cognitive benefits you need without worrying about potential interactions or side effects.
What Are the Benefits of Over-the-Counter Nootropics?
The benefits of taking over-the-counter nootropics are numerous. These supplements improve mental clarity, focus, memory formation, and recall.
Additionally, some can increase energy levels and improve reaction time and logical processing capabilities, which are beneficial when needing to stay sharp throughout any task or activity!
They can also help protect the brain against environmental stressors and aging. Choosing easily available nootropics, OTC, also means that you don't need a prescription from your doctor to benefit from their cognitive-enhancing properties.
Here's a quick overview of the best over-the-counter nootropics and their benefits:
Nooceptin - Improved mental clarity and focus, enhanced memory formation and retention, increased energy levels.
L-Theanine - Improved mood, reduced stress, and anxiety, improved focus and mental clarity.
Creatine - Enhanced memory formation, enhanced nerve impulses in the brain, better thinking processes.
Rhodiola Rosea - Increased alertness and concentration, improved physical performance during exercise.
Panax Ginseng - Improved brain energy levels and enhanced physical and mental performance.
Bacopa Monnieri - Enhanced memory formation, improved learning capacity, and increased antioxidant protection against aging.
What Are the Side Effects of Over-the-Counter Nootropics?
When taken in proper doses, the side effects of over-the-counter nootropics are usually mild and temporary.
However, excessive supplement intake can result in unpleasant side effects such as headaches, nausea, racing heartbeats, and insomnia.
It is important to consult your doctor before taking any supplements to ensure you’re not at risk of any adverse reactions or negative health effects.
Also, be mindful of the ingredients used in nootropic blends, as some may contain illegal or banned drugs in certain countries.
Do Over-the-Counter Nootropics Really Work?
So do I personally think that over-the-counter nootropics work? Yes. I have seen firsthand the cognitive benefits they can provide.
Although OTC nootropics are natural and readily available from most health stores, that doesn't mean they can’t be powerful cognitive-enhancing agents.
The key is to research, find the best nootropics for your needs, and use them responsibly to enjoy their full potential!
Taking a proactive approach and carefully researching each supplement before using it can ensure you get the most out of your nootropic supplement regimen.
Final Thoughts
What do we know about the best over-the-counter nootropics?
We know that OTC nootropics can provide you with a range of cognitive benefits, such as improved mental clarity and focus, enhanced memory formation and recall, increased energy levels, improved reaction time, better logical reasoning skills, and more.
We also know to be mindful of potential side effects and to speak with our doctor before using any supplements.
Finally, we also understand that taking a proactive approach and researching each supplement before use can ensure you get the most out of your nootropic experience.
These over-the-counter nootropics may be the key to unlocking your potential if used responsibly and safely!
I hope this article has given you a better understanding of the best over-the-counter nootropics available. With the right research and responsible use, these supplements can help you improve cognitive performance and reach peak mental acuity.
Best of luck on your journey to success—your brain will thank you!
Fluorophenibut, also known as F-phenibut or 4-Fluorophenibut, is a Nootropic that was originally developed in Russia to promote brain health and cognitive function.
It has been used for many years now as a way of treating people with conditions like sleep disorders and insomnia.
In this article, I'll be talking about the many other benefits of using Fluorophenibut and how it can be used by anyone who wants to improve their own mind, body, mood, or general sense of well-being.
So without further ado, let's just jump straight into it, shall we?
What is Fluorophenibut (F-Phenibut)?
Fluorophenibut (F-Phenibut) is a synthetic derivative of the neurotransmitter GABA (gamma-aminobutyric acid).
The neurochemical precursor for F-phenibut, phenyl - gamma-aminobutyric acid (or fenibut), was discovered in Russia during the 1960s.
It has since been used as a pharmaceutical drug to treat anxiety, insomnia, and other sleep disorders.
It has also been used in Russia for the treatment of alcoholism because it reduces withdrawal symptoms like delirium tremens (DTs).
Since its release on the market, F-phenibut has become increasingly popular among Russian bodybuilders and athletes looking to improve their mood, memory, focus, and overall well-being.
Fluorophenibut is a GABA derivative with fluorine substitution which allows it to pass through the blood-brain barrier more easily than other GABA analogs.
This means that Fluorophenibut has better effects on the Central Nervous System (CNS) compared to other related GABA-like compounds like Phenibut or Baclofen.
Fluorophenibut is capable of crossing the blood-brain barrier at a greater rate than regular Phenibut, meaning it can get to work more quickly and effectively after ingestion.
One thing that makes F-phenibut so popular is that it has a half-life of approximately 4 hours, which is shorter than Phenibut's eight-hour half-life.
This means that the effects are felt more rapidly and usually wear off sooner as well.
What Are The Effects Of Fluorophenibut?
Now before we get into any specific benefits or uses for Fluorophenibut, I just want to give you a quick rundown on how it works and affects the body.
F-phenibut has been shown to be very effective at improving mood, increasing sociability, and increasing pro-social behavior in social situations.
In other words, if you have anxiety or depression that interferes with your ability to go out and socialize, Fluorophenibut can help you feel more positive and sociable while still in a situation.
Fluorophenibut is also known for its strong anxiolytic effects which allow it to be helpful at reducing anxiety and stress levels.
It also has sedative properties which can help promote sleep and relaxation.
In addition, Fluorophenibut is thought to have anti-convulsive properties which could make it helpful for people who suffer from epilepsy or other seizure disorders.
It has also been shown to be an effective way of helping recovering alcoholics reduce their withdrawal symptoms like delirium tremens (DTs).
As I mentioned earlier, one of the key benefits of using Fluorophenibut is that it has a much shorter half-life than regular Phenibut.
This means that you can take smaller doses more frequently throughout the day. In fact, some users report being able to split their daily dosage into 2 or 3 doses throughout the day.
In my experience, I found that taking a dose of 400-500mg 2 or 3 times during the day was effective for giving me an overall feeling of well-being and improved mood.
How Does Fluorophenibut Compare To Phenibut?
Now I know what you're thinking, if Fluorophenibut is so much better than regular Phenibut then why would anybody ever use the latter?
Well, it all comes down to dosage.
Fluorophenibut has a half-life of approximately 4 hours, but Phenibut has a half-life of about eight hours.
Because of the shorter half-life, you need to take less Fluorophenibut compared to regular Phenibut in order to experience similar effects.
Fluorophenibut is actually much stronger per milligram than regular Phenibut so keep this in mind when dosing!
What Are The Side Effects Of Fluorophenibut?
When it comes to side effects, Fluorophenibut is thought to be quite well tolerated with few potential risks or drawbacks.
Some users have reported that it can cause sleep disruption and mild stomach discomfort if not taken with food.
It's also worth noting that because Fluorophenibut has a half-life of around five hours, it's going to accumulate in your system over time.
So if you take a dosage of 500mg, expect that at around the 4-hour mark, you're going to have 250mg in your system which will make it stronger and stay with you longer compared to taking a lower dose more frequently throughout the day.
The Wonderful Mind-Enhancing Effects of Fluorophenibut
Fluorophenibut has been shown to have a variety of effects in addition to providing mood enhancement and anxiety relief.
These include providing a sense of general well-being, decreased feelings of stress and anxiety, sleep promotion, and reduction in the symptoms of alcohol withdrawal.
Fluorophenibut also has anti-convulsive properties which could be helpful for individuals who suffer from seizure disorders or epilepsy.
For individuals who want an overall feeling of well-being and improved mood, Fluorophenibut can be very effective when taken in smaller doses throughout the day.
The other benefit is that it's available in oral and powder form so you can easily split your dosage into multiple periods throughout the day if desired.
In Conclusion
Fluorophenibut is a great alternative to regular Phenibut with a shorter half-life and has been shown to provide benefits that include mood enhancement, anxiety relief as well as providing an overall feeling of wellbeing.
Also keep in mind that because it's considered much stronger per milligram compared to regular Phenibut, you'll need to adjust your dosage accordingly.
Last but not least, Fluorophenibut has a half-life of around 4 hours so accumulation is likely whereas Phenibut has a much longer half-life which means you won't accumulate as quickly with it.
If you're ready to give Fluorophenibut a try, make sure you purchase it from a reputable vendor.
It's also recommended that if this is your first time trying out any nootropic supplements, start with the lowest dosage possible and work your way up over time in order to avoid unwanted side effects.
