Triacetyluridine Guide: What Are The Benefits & Side Effects?

Triacetyluridine, or TAU, is a nootropic that converts to Uridine in the body. It's proven to help alleviate the symptoms of depression by increasing dopamine levels in the brain.

If you've just recently come across Triacetyluridine you might have been wondering what exactly this relatively popular Nootropic is, what it does and if it has any potential side effects/benefits?

In this article I will take a closer look at the following topics:

• What is Triacetyluridine?
• What are the benefits and side effects?
• What's the best dosage?
• Can you stack it with other Nootropics?
• What are people on Reddit saying about?
• Where can you buy it?

... So without further ado, let's just jump straight to it, shall we?

What Is Triacetyluridine & How Does It Work?

As briefly mentioned in the beginning Triacetyluridine converts to Uridine in the body. Uridine is just one of the five standard nucleosides. The other four are;

1. Cytidine
2. Guanosine
3. Adenosine
4. Thymidine

When Triacetyluridine converts to Uridine Triphosphate in the body it can deliver up to 6 time as much uridine than just consuming uridine alone.

Uridine is a precursor of ribonucleic acid which supports healthy functioning of the central nervous system.

Clinically, Triacetyluridine is used in the treatment of fluorouracil overdose or toxicity. I found a study about Triacetyluridine right here where they show the efficacy in treating fluorouracil overdoses.

It's worth noting that Triacetyluridine received an FDA approval in 2015.

Triacetyluridine is found to activate the P2Y₂ receptors in the brain. This study shows that the P2Y₂R plays a neuroprotective role during inflammation in the CNS.

The reason why people are using Triacetyluridine as a Nootrpic is because it enhances functioning in synaptic connections and improves mitochondrial functioning. 

What Are The Benefits And Side Effects?

The data on potential benefits and side effects when taking Triacetyluridine is well documented.

From the studies I could find about Triacetyluridine here's what they show:

• It alleviates symptoms of depression and bipolar disorder
• It promotes an overall sense of well-being (enhances mood)
• It has anti-inflammatory and neuroprotective properties

In terms of side effects I couldn't really find any conclusive evidence since Triacetyluridine is generally well-tolerated.

The reason being that Triacetyluridine converts to Uridine in the body. Uridine is found in breast milk and is natural compound produced in humans.

This is why the side effects are rare. However, I did find some cases where people have taken high doses and reported vomiting, nausea, and diarrhea.

What About Dosages?

From what I could find on various forums people take anywhere from 25 mg to 100 mg of Triacetyluridine.

A low dose is generally considered to be 25mg and 100mg is considered to be a high dose.

Triacetyluridine comes in both powder form and capsules. 1 capsule is 25 mg.

Some people report that even 12mg of Triacetyluridine is sufficient when stacked with racetams such as;

• Fasoracetam
• Coluracetam
• Aniracetam

As is the case with most Nootropics, it's always a good idea to start off with a low dose to access its effects on your body/mental health.

If it's your first time trying Triacetyluridine I wouldn't recommend stacking it with other Nootropics either until you're 100% certain that it doesn't have any negative side effects.

Triacetyluridine vs Uridine Monophosphate

There isn't too much of a difference between Triacetyluridine and uridine monophosphate.

That being said Triacetyluridine is more potent and has a higher bioavailable when it comes to Uridine compared to Uridine Monophosphate.

Both supplements have the same effects and can take anywhere from 1 to 3 hours to kick in.

What Are People On Reddit Saying?

Triacetyluridin & Depression

The first thread on Reddit I could find is from a user called; u/utsukushii_rei.

Utsukushii says that he just recently bought Triacetyluridine and has been getting really great results but is curious to know if stacking it with anti-depressants is a bad idea.

He then goes on to say that after taking Triacetyluridine his memory is much sharper and his mood has improved quite a bit.

He then finishes off by asking the following question:

"My question is would combining my daily anti depressants be a bad idea?"

Triacetyluridin, when converted in the body, has a direct impact on serotonin and dopamine (so would make sense why he is asking this question.)

Utsukushii doesn't get any definitive answer from people in the thead, so I'll try to answer it here:

A good rule of thumb is to NEVER combine nootropics with SSRI's unless your doctor says otherwise. Do NOT play around with your brain chemistry.

Triacetyluridine vs UMP - Which One Is Better?

Another thread I found on Reddit is from a user called; u/jt2424.

He's starting out by asking which one is better; Triacetyluridine or Uridine Monophosphate?

He then goes on to say that he only has tried Triacetyluridine (he takes 25-50mg) which seems to make his mood better and more social.

A user called; FrigoCoder, is then replying saying that he prefers Triacetyluridine because the benefits are immediate and more noticeable.

FrigoCoder then goes on to say the following:

" I do not think I have ever benefited from Uridine Monophosphate. "

Triacetyluridine & Quitting Smoking

The last thread I could find, and an interesting one, is from a user called; U/srubek.

Interesting enough he is talking about Triacetyluridine and smoking.

He starts off by saying how he never though that he would quit smoking. He goes on to say the following:

"I was ruining my lungs and I was having so much trouble breathing. I had tried everything."

He then came across Triacetyluridine.

He took 25mg/day every morning and noticed how he could bear working with only 1 cigarette break.

U/srubek tried vaping but compared to Triacetyluridine (TAU), TAU never left him wanting cigarettes.

The then states the following:

"I was amazed. I still am, tbh. 1.5 years cigarette-free, and healthy af"

He then goes on to say that people from work have made comments about his skin quality (asking what he did).

"I appeared shiny, smooth, clear, healthy."

The thread is extremely detailed so if you're thinking about quitting smoking I can highly recommend reading the entire thread here (U/srubek is going into much more details).

Where Can I Buy Triacetyluridine?

You can find Triacetyluridine on most Nootropic websites. TAU is sold in both powder form and capsules.

I only buy from one vendor which is called; NootropicsDepot. The reason being they lab test their products to ensure high quality and purity.

They also have a lot of reviews from verified buyers which is always a good thing.

Their powder comes in 10, 25 and 50 grams. You can find it here.

They also have 25mg capsules - you can find them right here.

The only downside I have experienced buying from NootropicsDepot is the delivery time.

I live in Europe and it usually takes anywhere from 8 to 13 business days for my package to arrive. Keep that in mind if you're in a hurry.

That being said I'm sure you can find a quicker shipping method at checkout.

In Conclusion

Triacetyluridine is converted to Uridine in the body.

It is used as a nootropic because it boosts cognition and supports healthy functioning of the central nervous system.

People who take it are experiencing better mood and an overall sense of well-being.

A low dose is considered to be in the 25-50mg range.

A high dose is considered to be 100mg.

Triacetyluridine seems to be safe with low side effects.

It can be bought in both powder form and capsules on most nootropics websites.

Triacetyluridine is very similar to uridine monophosphate but is more potent and kicks in faster.

Lastly, some people use TAU to quit smoking.

source https://nootropicology.com/triacetyluridine-review/

Primavie Shilajit: What You Need To Know Before Buying (My Experience)

Primavie Shilajit is a natural occurring compound found in the Himalayas. Shilajit is known to boost energy and testosterone levels.

Hey Guys!

If you've been in the Nootropic-space for some time you should know by now what Primavie Shilajit is.

If you don't, or you just simply want to find out more information about it, then this article is for you.

The information I share in this article will be based on my own personal experience and what the science says.

I will also try to see if I can find some anecdotes from people on Reddit to give a more nuanced picture of the benefits and side-effects that people are experiencing when taking Primavie.

Here are some of the topics I will be covering in today's article:

• What is Primavie Shilajit?
• How does it work?
• How do you take it and how much should you take?
• What are the benefits and side-effects?
• What are people on Reddit saying about it?
• Where can I buy it?

...... So without further ado, let's just jump straight to it!

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What Is Primavie Shilajit & How Does It Work?

Primavie Shilajit is traditionally considered to be a divine medicine. It has been used for centuries in ancient cultures as a herbal for healing and vitality.

Due to its profound adaptogenic health benefits, and anti-aging powers, we have discovered (just recently) by combining this ancient knowledge with modern science that it derives its benefits by enhancing the upregulation of the collagen genes in our skeletal muscles.

This is why we can see that consumption Primavie Shilajit improves blood flow to the skin, testosterone levels in men, increases energy levels as well as supporting bone health.

I will talk more about the benefits later on in this article. But for now, let's just continue with some more background information.

Shilajit is a naturally occurring resin. A resin is just a solid substance from a plant.

It is found high in the Himalayan mountains as an organic substance containing a mixture of fulvic acid, minerals and other organic minerals.

It is then extracted and turned into an extraordinary Himalayan superfood and sold as Primavie Shilajit.

As I briefly stated above, Primavie Shilajit contains A LOT of different organic minerals. All of these minerals play a crucial role when it comes to improving our overall health.

Interesting enough it also has a profound effect on testosterone levels which I find fascinating.

I came across a randomised, double-blind, placebo-controlled clinical study where they measured the effects that Primavie Shilajit has on testosterone levels.

In the experiment they used purified Shilajit in healthy volunteers of age between 45 and 55 years.

What they found was that a treatment with Shilajit for 90 days in total, revealed that it has a significant effect on testosterone levels.

It increased total testosterone, free testosterone and dehydroepiandrosterone (DHEAS) compared with placebo.

You can find the study right here.

What Are The Benefits & Side Effects?

As I have already alluded to earlier Primavie Shilajit has a lot of benefits. I will list the benefits right below which will be a combination of what I could find in the literature as well as from my own experience.

The most commonly reported benefits are:

• Improved sleep quality
• Increased testosterone levels
• Improved energy levels
• Improved mood
• Enhanced cognition (better focus, more alertness and mental energy)

In terms of side-effects I couldn't really find any conclusive evidence/anecdotes that found anything noteworthy.

My Personal Experience With Primavie Shilajit

I can definitely attest to the cognitive benefits that people are reporting experiencing when taking Primavie Shilajit.

I ordered the 30gr powder from NootropicsDepot and have been using it for 9 days now.

Although it's only been 9 days one of the things that I noticed almost instantly (could be placebo though?) is the effect it has on my mood.

I think it's safe to say that I'm a person that tends to be on the more 'neurotic side' of the spectrum (dealing with social anxiety etc.).

What I have found is not that Primavie Shilajit has a 'calming effect' on me per se but it gives me the mental and physical energy to get stuff done.

It's hard to describe but I feel like it gives me a subtle drive and groundedness to make things happen as well as an overall sense of well-being which especially has helped me out at social events.

The benefits I experience taking Primavie Shiljit is very similar to the benefits I get on Ashwagandha.

So to summarize, here's the benefits I personally have experienced taking Primavie Shiljit

• I have way more mental energy (I can think clearly and my memory has improved)
• I feel a subtle 'groundedness' that has been EXTREMELY useful in social situations (dealing with social anxiety)
• I have noticed positive improvements in terms of mental- and physical energy (I want to make things happen)
• I feel less fatigued at the end of the day

In terms of fatigue, one thing that I have noticed is that I'm not mentally exhausted in the evening anymore.

This is the benefit that actually has been the most noticable.

I work a 9-5 job and will usually be exhausted by the time I get home. To put this into perspective I usually try to write an article for Nootropicology early in the morning because I know writing in the evening is a no-go for me.

After taking Primavie Shiljit I have actually changed my schedule. I now only write in the evening which is a HUGE deal for me.

Keep in mind I have only used it for 9 days so the benefits I have experienced thus far could just be a placebo effect, but whocares if it works, right :-)?!

Primavie Shilajit And Weight Training

Since I don't really work out anymore I can't give you guys an in-depth insight to the effects it has on weight training.

That being said, I did find a couple of YouTube videos with people who are doing weight training and using Primavie Shilajit.

The first video I could find is from a guy named; Tiger Fitness. He almost has 400k subscribers.

Here's what he's saying about Primavie Shilajit its effects on training, testosterone and libido:

Another guy called; The Nootropic Republic is sharing his own experience with Primavie Shilajit here:

https://www.youtube.com/watch?v=j8bAnr4y290&t=65s

The Nootropic Republic is basically saying how great of an impact Primavie has had on his exercise performance.

He then goes on to say that it has been shown to help you lift more in the gym. Whether you want to improve your bench, squat, deadlift etc. Primavie can have a beneficial effect on those goals.

He then goes on to say that he personally can notice a difference in his lift as well as feeling more powerful or 'dynamic' as he puts it.

He finishes off by saying that his recovery in the gym is shorter and how Primavie has helped improve his muscle density and muscle strength.

I would imagine that Primavie could help with the pump as well since it's proven to increase blood flow to the muscle (one of you guys would have to test that out for yourself and report back to me).

Read Also: What is Dynamine Methylliberine?

How Do You Take It & What Does It Taste Like?

A question I often see on forums is; What does Primavie Shilajit taste like? First off, it's important to note that there are different grades of this compound.

Typically the darker powders are stronger in flavor with a somewhat 'earthy' bitter taste.

The powder I bought doesn't have that strong of a taste. That being said it does taste a little weird, but it's something you get used to.

This might not sound appealing for most of you guys but whocares, it's a 'superfood' so I just chug it down.

The way you take Primavie Shilajit is by blending it into hot drinks, shake or just put it in a glass of water and chug it down.

That being said, Primavie Shilajit is traditionally consumed with raw milk in parts of North India, Pakistan, and Nepal.

For those of you who don't enjoy the taste of the powder Primavie Shilajit can be consumed as capsules as well.

What's The Right Dosage?

As is the case with most Nootropics and supplements the dose you should take really comes down to your personal goals, body weight and tolerance.

That being said from the information I could find online prior to buying it, a regular dose is 250 mg once a day which is equivalent to 1 capsule if you buy Primavie Shilajit from NootropicsDepot.

I personally started out with 125mg (half a capsule) to measure any potential side-effects. I didn't notice anything and gradually increased my daily intake to 2 capsules (500mg) which seems to be the sweet-spot for me.

It's impossible to overdose on this mineral powder and it is known to be safe, to consume over a long period of time.

It should, however, be avoided when pregnant and it's always a good idea to get the advice of your healthcare provider when taking any supplement.

Where Can I Buy It?

Since Primavie Shilajit is a natural compound you can find it pretty much anywhere on the internet.

It comes in both powder form and capsules.

I only have experience buying Nootropics from Science.bio. The reason being they lab test their products to ensure that each batch is high in quality and purity.

I live in Europe and it took 9 business days to arrive using the standard shipping method.

What Do People On Reddit Say About Primavie Shilajit?

I came across a couple of interesting threads on Reddit. One in particular caught my eyes.

I thought it would be a good idea for me to share everything here. Hopefully you guys, like me, get some value out of this.

The first Reddit thread I found is from a user called; u/Bobz216.

He starts off his thead by stating that Primavie Shilajit is NOT some snake oil.

Bobz216 then goes into his own personal experience with the mineral. The first thing he has noticed after taking Primavie Shilajit for a couple of days is the boost in cognition. He says:

"I have been taking shilajit for a couple days now, and notice an immense boost in my cognition and energy.."

Bobz216 has bought his Primavie Shilajit from NootropicsDepot which is purified (it doesn't put him in risk of heavy-metal poisening).

Interesting enough he also talks briefly about its altering effects;

"This substance exhibits strong subjective feelings and a sense of altered consciousness..."

Like myself, Bobz216 has noticed his lethargy is reduced greatly and energy is increased. He also states that the energy he gets from Primavie Shilajit feels 'natural' unlike caffeine etc.

Bobz216 also notices the effects on his libido or as he puts it:

"My sex drive, which has been an issue for me in the past thanks to PSSD from Lexapro, seems to have increased greatly as well. "

He then goes on to say that he feels more 'in the moment' when he has sex as well as lasting longer.

Bobz216 states that he has OCD and how effective Primavie Shilajit has been on his logical thinking. He finds his inner voice to be 'clearer' and is able to differentiate between obsessive and rational thoughts.

He finishes off by saying that he bought Primavie Shilajit not under the impression that it was going to exhibit any psychoactive effects (he bought it for the purported sexual effects) but was pleasantly surprised by the mental benefits he experienced on it.

In Conclusion

Primavie Shilajit is a natural occurring herb found in the Himalayas.

Shilajit is known to boost energy and testosterone levels as well as libido.

People are reporting increased energy levels, better focus, more clearity and vitality consuming it with no side effects.

From my own experience I can attest to the fact that Primavie Shilajit has had a profound effect on my mental health.

I have experienced more mental- and physical energy. A subtle groundedness that has been extremely beneficial in social situations.

Primavie Shilajit is legal and can be bought from most Nootropic Vendors online.

source https://nootropicology.com/primavie-shilajit-review/